Designation:D7645−16StandardTestMethodforDeterminationofAldicarb,AldicarbSulfone,AldicarbSulfoxide,Carbofuran,Methomyl,Oxamyl,andThiofanoxinWaterbyLiquidChromatography/TandemMassSpectrometry(LC/MS/MS)1ThisstandardisissuedunderthefixeddesignationD7645;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thisprocedurecoversthedeterminationofaldicarb,aldicarbsulfone,aldicarbsulfoxide,carbofuran,methomyl,oxamyl,andthiofanox(referredtocollectivelyascarbamatesinthistestmethod)inwaterbydirectinjectionusingliquidchromatography(LC)anddetectedwithtandemmassspec-trometry(MS/MS).Theseanalytesarequalitativelyandquan-titativelydeterminedbythistestmethod.Thistestmethodadherestomultiplereactionmonitoring(MRM)massspec-trometry.1.2TheDetectionVerificationLevel(DVL)andReportingRangeforthecarbamatesarelistedinTable1.1.2.1TheDVLisrequiredtobeataconcentrationatleast3timesbelowtheReportingLimit(RL)andhaveasignal/noiseratiogreaterthan3:1.Fig.1displaysthesignal/noiseratiosoftheprimarysinglereactionmonitoring(SRM)transitions,andFig.2displaystheconfirmatorySRMtransi-tionsattheDVLsforthecarbamates.1.2.2ThereportinglimitistheconcentrationoftheLevel1calibrationstandardasshowninTable2forthecarbamates.1.3Units—ThevaluesstatedinSIunitsaretoberegardedasstandard.Nootherunitsofmeasurementareincludedinthisstandard.1.4Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.2.ReferencedDocuments2.1ASTMStandards:2D1129TerminologyRelatingtoWaterD1193SpecificationforReagentWaterD2777PracticeforDeterminationofPrecisionandBiasofApplicableTestMethodsofCommitteeD19onWaterD3694PracticesforPreparationofSampleContainers...
