Designation:E1053−11StandardTestMethodtoAssessVirucidalActivityofChemicalsIntendedforDisinfectionofInanimate,NonporousEnvironmentalSurfaces1ThisstandardisissuedunderthefixeddesignationE1053;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thistestmethodisusedtoevaluatethevirucidalefficacyofliquid,aerosol,ortrigger-spraymicrobicidesin-tendedforuseoninanimate,nonporousenvironmentalsur-faces.Thistestmethodmaybeemployedwithmostviruses,whichcanbegrowninculturedcells.2However,otherhostsystems(forexample,embryoniceggs)maybeusedwithproperjustificationanddocumentation.1.2Thistestmethodshouldbeperformedonlybythosetrainedinmicrobiologicalandvirologicaltechniquesinfacili-tiesdesignedandequippedforworkwithinfectiousagentsattheappropriatebiosafetylevel.1.3ItistheresponsibilityoftheinvestigatortodeterminewhetherGoodLaboratoryPracticeregulations(GLPs)arerequiredandtofollowthemwhereappropriate(40CFR,Part160forEPAsubmissionsand21CFR,Part58forFDAsubmissions).Refertotheappropriateregulatoryagencyforperformancestandardsofvirucidalefficacy.1.4Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.Theusershouldconsultareferenceforlaboratorysafetyrecommendations.22.ReferencedDocuments2.1ASTMStandards:3D1129TerminologyRelatingtoWaterE1153TestMethodforEfficacyofSanitizersRecommendedforInanimateNon-FoodContactSurfacesE1482TestMethodforNeutralizationofVirucidalAgentsinVirucidalEfficacyEvaluationsE2197QuantitativeDiskCarrierTestMethodforDetermin-ingBactericidal,Virucidal,Fungicidal,Mycobactericidal,andSporicidalActivitiesofChemicals2.2FederalStandards:4Title21,CodeofFederalRegulations(CFR),Foodan...
